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Description
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Current research on the pathophysiological mechanisms of
brain trauma is at the vanguard of neuroscience research. Clinical trials
in head trauma are being conducted to determine the potential
effectiveness of numerous drugs, with major results projected over
the next few years. Unfortunately, no existing book presents the
topic of head trauma with both a summary of the science and an
extension of these findings into clinical applications. Head Trauma:
Basic, Preclinical, and Clinical Directions fills the void in the
literature on this subject.
Providing an overview of the major modalities in head trauma
therapeutics, this book not only offers a comprehensive presentation
of the science in this area but also contains the most up-to-date
discussion regarding the basis for experimental and clinical
pharmacological treatment of head trauma. Chapters cover basic
mechanisms, preclinical targets, clinical aspects with information on
efficacy studies, and a straightforward, easy-to-follow presentation
of the side effects and potency ratios. In addition, a list of major
Web sites of interest and importance to neurotrauma researchers is included.
Additional topics reviewed in Head Trauma: Basic, Preclinical, and
Clinical Directions include:
* In vitro models of traumatic brain injury
* Receptor-based mechanisms in head trauma
* Mitochondrial dysfunction following traumatic brain injury
* Epidemiology and economics of head trauma
* Guidelines for medical and surgical management of head trauma
patients used throughout the world
* Perspectives on the future of head trauma therapeutics
* And much more
With this book, neurosurgeons, neurologists, neurophysiologists, and
neuroscientists now have a definitive reference on the subject of
head trauma.
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